藥品參考
Temoporfin
Temoporfin is a medicine in the class oncology. It is used for head & neck cancer.
- 藥物類別: Oncology
- 用途: head & neck cancer
最後更新 來源: EMA SmPC
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
重點資訊
- 藥物類別
- Oncology
- ATC 代碼
- L01XD05
- 已知交互作用
- 1 (中度: 1)
- 商品名
- 1
- 國家與市場
- 1
用途
作用方式
Photosensitising agent for photodynamic therapy. Photoactivation with non-thermal light at 652 nm after intravenous administration generates highly reactive oxygen species through interaction of temoporfin with light and oxygen.
成人常用劑量（仿單摘要）
Repeat course: a second course may be given at the physician's discretion, with a minimum interval of 4 weeks between treatments
懷孕與哺乳
- 懷孕
- Unsafe No human data; animal studies showed reproductive toxicity. Do not use in pregnancy unless clinically required. Use effective contraception during and up to 3 months after treatment.
- 哺乳
- Unsafe Unknown whether excreted in human milk; risk to infants cannot be excluded. Discontinue breast-feeding for at least one month after injection.
已通報的副作用
- Haemorrhage
- Constipation
- Dysphagia
- Necrotising stomatitis
- Pain in the photoactivated area
- Injection site pain
禁忌症
- Hypersensitivity to the active substance or excipients
- Porphyria or other diseases exacerbated by light
- Hypersensitivity to porphyrins
哪些人需要特別留意
- All patients become temporarily photosensitive; avoid direct sunlight and bright indoor light for the first 15 days. UV sunscreens give no protection.
- Local photoactivation toxicity may damage surrounding tissue, causing fistula, perforation, vascular rupture, infection and sepsis; shield normal tissue.
- Prevent extravasation; if it occurs, protect the area from light for at least 3 months
請告知藥師或醫師您是否懷孕或哺乳、是否患有腎臟或肝臟疾病、是否有過敏，以及您正在使用的所有其他藥物或保健品。
重要交互作用 (1)
- Fluorouracil + Temoporfin Moderate
同類別的其他藥品
常見問題
What is Temoporfin used for?
Temoporfin is a medicine in the class oncology. It is used for Head & neck cancer, Squamous cell carcinoma.
What side effects have been reported with Temoporfin?
Haemorrhage, Constipation, Dysphagia, Necrotising stomatitis, Pain in the photoactivated area, Injection site pain.
Can Temoporfin be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. No human data; animal studies showed reproductive toxicity. Do not use in pregnancy unless clinically required. Use effective contraception during and up to 3 months after treatment. Breastfeeding: Unsafe. Unknown whether excreted in human milk; risk to infants cannot be excluded. Discontinue breast-feeding for at least one month after injection.
What does Temoporfin interact with?
MediHelp lists 1 known interactions for Temoporfin. Moderate: 1. The most serious include Fluorouracil.
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