藥物交互作用
Abatacept + Dengue vaccine
嚴重程度: 嚴重
Abatacept and Dengue vaccine: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Dengue vaccine (Dengvaxia) is a live attenuated vaccine, so it carries a risk of vaccine-related infection in immunosuppressed people. Abatacept may also reduce the immune response to the vaccine.
用白話說明這項交互作用的意義
Abatacept and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Immunosuppression impairs control of live attenuated virus replication and reduces vaccine immunogenicity.
處置方式
Avoid live vaccines during abatacept therapy and for several weeks after the last dose, which is roughly 3 months. Consider vaccination before starting treatment.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Abatacept 的其他交互作用
常見問題
Can I take Abatacept with Dengue vaccine?
MediHelp rates the interaction as major. Abatacept and Dengue vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dengue vaccine (Dengvaxia) is a live attenuated vaccine, so it carries a risk of vaccine-related infection in immunosuppressed people. Abatacept may also reduce the immune response to the vaccine.
How serious is the interaction between Abatacept and Dengue vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during abatacept therapy and for several weeks after the last dose, which is roughly 3 months. Consider vaccination before starting treatment.
What other medicines interact with Abatacept?
MediHelp also lists interactions of Abatacept with, for example, Adalimumab, Adenovirus types 4 and 7 live, Anakinra. The full list is on the Abatacept page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
