藥物交互作用
Abciximab + Antithrombin iii
嚴重程度: 嚴重
Abciximab and Antithrombin iii: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Antithrombin III enhances endogenous anticoagulation while abciximab blocks platelet aggregation, so combined use markedly increases bleeding risk. Hemorrhage may be serious.
用白話說明這項交互作用的意義
Abciximab and Antithrombin iii can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive pharmacodynamic effect of platelet GP IIb/IIIa blockade and enhanced inhibition of thrombin and factor Xa.
處置方式
Avoid unless clearly indicated; if used, monitor aPTT or anti-Xa, platelet counts and bleeding signs closely.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Abciximab 的其他交互作用
常見問題
Can I take Abciximab with Antithrombin iii?
MediHelp rates the interaction as major. Abciximab and Antithrombin iii can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Antithrombin III enhances endogenous anticoagulation while abciximab blocks platelet aggregation, so combined use markedly increases bleeding risk. Hemorrhage may be serious.
How serious is the interaction between Abciximab and Antithrombin iii?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unless clearly indicated; if used, monitor aPTT or anti-Xa, platelet counts and bleeding signs closely.
What other medicines interact with Abciximab?
MediHelp also lists interactions of Abciximab with, for example, Abrocitinib, Acalabrutinib, Acetylsalicylic acid. The full list is on the Abciximab page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
