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藥物交互作用

Acarbose + Cortisone

嚴重程度: 中度

Acarbose and Cortisone: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Systemic corticosteroids such as cortisone raise blood glucose and can offset the glucose-lowering effect of acarbose. Patients with diabetes may experience worsened glycemic control, particularly with prolonged or higher-dose corticosteroid courses.

用白話說明這項交互作用的意義

Acarbose and Cortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

證據等級: High

為什麼會發生

Corticosteroids increase hepatic gluconeogenesis and cause peripheral insulin resistance, opposing the antihyperglycemic action of acarbose.

處置方式

Monitor blood glucose more frequently when starting, increasing or stopping cortisone, and adjust the antidiabetic regimen as needed. Reduce doses again when the corticosteroid is tapered to avoid hypoglycemia.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Acarbose with Cortisone?

MediHelp rates the interaction as moderate. Acarbose and Cortisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic corticosteroids such as cortisone raise blood glucose and can offset the glucose-lowering effect of acarbose. Patients with diabetes may experience worsened glycemic control, particularly with prolonged or higher-dose corticosteroid courses.

How serious is the interaction between Acarbose and Cortisone?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more frequently when starting, increasing or stopping cortisone, and adjust the antidiabetic regimen as needed. Reduce doses again when the corticosteroid is tapered to avoid hypoglycemia.

What other medicines interact with Acarbose?

MediHelp also lists interactions of Acarbose with, for example, Pramlintide, Asenapine, Bitter melon. The full list is on the Acarbose page.

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