藥物交互作用
Acetaminophen / phenyltoloxamine + Brivaracetam
嚴重程度: 中度
Acetaminophen / phenyltoloxamine and Brivaracetam: moderate interaction.
最後更新
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摘要
Phenyltoloxamine is a sedating first-generation antihistamine, and brivaracetam commonly causes somnolence and dizziness. Taken together, drowsiness and impaired psychomotor performance may be greater than with either drug alone.
用白話說明這項交互作用的意義
Acetaminophen / phenyltoloxamine and Brivaracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Additive central nervous system depression from two sedating agents.
處置方式
Warn the patient about increased drowsiness and advise against driving or operating machinery until the response is known. Prefer a non-sedating analgesic or antihistamine if sedation becomes troublesome.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Brivaracetam 的其他交互作用
常見問題
Can I take Acetaminophen / phenyltoloxamine with Brivaracetam?
MediHelp rates the interaction as moderate. Acetaminophen / phenyltoloxamine and Brivaracetam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Phenyltoloxamine is a sedating first-generation antihistamine, and brivaracetam commonly causes somnolence and dizziness. Taken together, drowsiness and impaired psychomotor performance may be greater than with either drug alone.
How serious is the interaction between Acetaminophen / phenyltoloxamine and Brivaracetam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Warn the patient about increased drowsiness and advise against driving or operating machinery until the response is known. Prefer a non-sedating analgesic or antihistamine if sedation becomes troublesome.
What other medicines interact with Brivaracetam?
MediHelp also lists interactions of Brivaracetam with, for example, Benzhydrocodone / acetaminophen, Sodium oxybate, Alfentanil. The full list is on the Brivaracetam page.
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