藥物交互作用
Adenovirus types 4 and 7 live + Daunorubicin
嚴重程度: 禁忌併用
Adenovirus types 4 and 7 live and Daunorubicin: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Daunorubicin is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine may fail to produce protection and could cause disseminated vaccine-strain infection. Live vaccines should not be given to patients on cytotoxic chemotherapy.
用白話說明這項交互作用的意義
Adenovirus types 4 and 7 live and Daunorubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
為什麼會發生
Immunosuppression from the cytotoxic agent impairs the immune response and allows the live attenuated virus to replicate uncontrolled.
處置方式
Do not give the live vaccine during chemotherapy or for at least 3 months after it ends. Check immune recovery before vaccination.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Daunorubicin 的其他交互作用
常見問題
Can I take Adenovirus types 4 and 7 live with Daunorubicin?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Daunorubicin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Daunorubicin is myelosuppressive and immunosuppressive, so a live oral adenovirus vaccine may fail to produce protection and could cause disseminated vaccine-strain infection. Live vaccines should not be given to patients on cytotoxic chemotherapy.
How serious is the interaction between Adenovirus types 4 and 7 live and Daunorubicin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give the live vaccine during chemotherapy or for at least 3 months after it ends. Check immune recovery before vaccination.
What other medicines interact with Daunorubicin?
MediHelp also lists interactions of Daunorubicin with, for example, Belatacept, Cyclosporine, Cyclosporin. The full list is on the Daunorubicin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
