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藥物交互作用

Alfentanil + Ziprasidone

嚴重程度: 中度

Alfentanil and Ziprasidone: moderate interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

Combining an opioid with an antipsychotic increases sedation, and can cause hypotension and respiratory depression. This matters most during procedural or perioperative use.

用白話說明這項交互作用的意義

Alfentanil and Ziprasidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

證據等級: Moderate

為什麼會發生

Additive CNS depression from opioid agonism and antipsychotic sedative and antihistaminic/alpha-blocking effects.

處置方式

Use reduced opioid doses and monitor sedation, respiratory rate and blood pressure.

可向藥師詢問的問題

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ 會員專屬

解鎖完整頁面

建立帳號並開始 Pro+ 試用,即可解鎖 Alfentanil 與 Ziprasidone 的完整臨床處置建議、補充說明、證據詳情及整張處方的交互作用檢查工具。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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常見問題

Can I take Alfentanil with Ziprasidone?

MediHelp rates the interaction as moderate. Alfentanil and Ziprasidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining an opioid with an antipsychotic increases sedation, and can cause hypotension and respiratory depression. This matters most during procedural or perioperative use.

How serious is the interaction between Alfentanil and Ziprasidone?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use reduced opioid doses and monitor sedation, respiratory rate and blood pressure.

What other medicines interact with Ziprasidone?

MediHelp also lists interactions of Ziprasidone with, for example, Amiodarone, Amitriptyline, Arsenic trioxide. The full list is on the Ziprasidone page.

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