藥物交互作用
Alogliptin-pioglitazone + Lonapegsomatropin
嚴重程度: 中度
Alogliptin-pioglitazone and Lonapegsomatropin: moderate interaction.
最後更新
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摘要
Growth hormone reduces insulin sensitivity, which can raise blood glucose and blunt the effect of alogliptin and pioglitazone. Patients with diabetes may need higher doses of their antihyperglycemic agents.
用白話說明這項交互作用的意義
Alogliptin-pioglitazone and Lonapegsomatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Alogliptin-pioglitazone belongs to Endocrine; Lonapegsomatropin belongs to Endocrine.
為什麼會發生
Pharmacodynamic antagonism through growth hormone-induced insulin resistance.
處置方式
Monitor blood glucose and HbA1c when starting or adjusting lonapegsomatropin. Adjust antidiabetic doses as required.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Alogliptin-pioglitazone 的其他交互作用
Lonapegsomatropin 的其他交互作用
常見問題
Can I take Alogliptin-pioglitazone with Lonapegsomatropin?
MediHelp rates the interaction as moderate. Alogliptin-pioglitazone and Lonapegsomatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Growth hormone reduces insulin sensitivity, which can raise blood glucose and blunt the effect of alogliptin and pioglitazone. Patients with diabetes may need higher doses of their antihyperglycemic agents.
How serious is the interaction between Alogliptin-pioglitazone and Lonapegsomatropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c when starting or adjusting lonapegsomatropin. Adjust antidiabetic doses as required.
What other medicines interact with Alogliptin-pioglitazone?
MediHelp also lists interactions of Alogliptin-pioglitazone with, for example, Gemfibrozil, Insulin aspart, Insulin degludec. The full list is on the Alogliptin-pioglitazone page.
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