藥物交互作用
Anagrelide + Cilostazol
嚴重程度: 嚴重
Anagrelide and Cilostazol: major interaction.
最後更新
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摘要
Both drugs are PDE3 inhibitors, so combining them may amplify cardiovascular effects such as tachycardia, palpitations, fluid retention and hypotension. Anagrelide labeling advises caution with other PDE3 inhibitors, and bleeding risk may also be additive.
用白話說明這項交互作用的意義
Anagrelide and Cilostazol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Anagrelide belongs to Cardiovascular; Cilostazol belongs to Cardiovascular.
為什麼會發生
Additive PDE3 inhibition producing enhanced inotropic, chronotropic, vasodilatory and antiplatelet effects.
處置方式
Avoid the combination where possible; if used, monitor heart rate, blood pressure, signs of heart failure and bleeding closely.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Cilostazol 的其他交互作用
Anagrelide 的其他交互作用
常見問題
Can I take Anagrelide with Cilostazol?
MediHelp rates the interaction as major. Anagrelide and Cilostazol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs are PDE3 inhibitors, so combining them may amplify cardiovascular effects such as tachycardia, palpitations, fluid retention and hypotension. Anagrelide labeling advises caution with other PDE3 inhibitors, and bleeding risk may also be additive.
How serious is the interaction between Anagrelide and Cilostazol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible; if used, monitor heart rate, blood pressure, signs of heart failure and bleeding closely.
What other medicines interact with Cilostazol?
MediHelp also lists interactions of Cilostazol with, for example, Abrocitinib, Betrixaban, Cobicistat. The full list is on the Cilostazol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
