藥物交互作用
Antithymocyte globulin rabbit + Echinacea
嚴重程度: 中度
Antithymocyte globulin rabbit and Echinacea: moderate interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Echinacea has immunostimulant properties in vitro and could theoretically blunt the T-cell depleting effect of rabbit antithymocyte globulin. This might reduce protection against rejection or graft-versus-host disease. Clinical evidence is lacking.
用白話說明這項交互作用的意義
Antithymocyte globulin rabbit and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
為什麼會發生
Theoretical pharmacodynamic antagonism between herbal immune stimulation and profound T-cell depletion.
處置方式
Advise transplant patients to avoid echinacea products during and after antithymocyte globulin therapy. Monitor for signs of rejection if the herb has been used.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Echinacea 的其他交互作用
常見問題
Can I take Antithymocyte globulin rabbit with Echinacea?
MediHelp rates the interaction as moderate. Antithymocyte globulin rabbit and Echinacea can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Echinacea has immunostimulant properties in vitro and could theoretically blunt the T-cell depleting effect of rabbit antithymocyte globulin. This might reduce protection against rejection or graft-versus-host disease. Clinical evidence is lacking.
How serious is the interaction between Antithymocyte globulin rabbit and Echinacea?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise transplant patients to avoid echinacea products during and after antithymocyte globulin therapy. Monitor for signs of rejection if the herb has been used.
What other medicines interact with Echinacea?
MediHelp also lists interactions of Echinacea with, for example, Alefacept, Antithymocyte globulin equine, Azathioprine. The full list is on the Echinacea page.
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