藥物交互作用
Baricitinib + Upadacitinib
嚴重程度: 禁忌併用
Baricitinib and Upadacitinib: contraindicated interaction.
最後更新
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摘要
Baricitinib and upadacitinib are both JAK inhibitors, so using them together duplicates therapy without proven benefit. Exposure to JAK-related adverse effects such as serious infection, thrombosis, cytopenias and lipid rise is doubled.
用白話說明這項交互作用的意義
Baricitinib and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Baricitinib belongs to Musculoskeletal; Upadacitinib belongs to Musculoskeletal.
為什麼會發生
Therapeutic duplication of JAK inhibition
處置方式
Do not combine; if switching between JAK inhibitors, stop the first agent before starting the second.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Baricitinib 的其他交互作用
Upadacitinib 的其他交互作用
常見問題
Can I take Baricitinib with Upadacitinib?
MediHelp rates the interaction as contraindicated. Baricitinib and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Baricitinib and upadacitinib are both JAK inhibitors, so using them together duplicates therapy without proven benefit. Exposure to JAK-related adverse effects such as serious infection, thrombosis, cytopenias and lipid rise is doubled.
How serious is the interaction between Baricitinib and Upadacitinib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; if switching between JAK inhibitors, stop the first agent before starting the second.
What other medicines interact with Baricitinib?
MediHelp also lists interactions of Baricitinib with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Tofacitinib. The full list is on the Baricitinib page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
