藥物交互作用
Benzhydrocodone / acetaminophen + Carisoprodol
嚴重程度: 嚴重
Benzhydrocodone / acetaminophen and Carisoprodol: major interaction.
最後更新
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摘要
Benzhydrocodone is an opioid prodrug of hydrocodone, and carisoprodol is a sedating muscle relaxant. Together they can produce profound sedation, respiratory depression, coma and death.
用白話說明這項交互作用的意義
Benzhydrocodone / acetaminophen and Carisoprodol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive CNS and respiratory depression from opioid and carisoprodol (via its meprobamate metabolite) effects.
處置方式
Avoid unless other options are inadequate; use the lowest doses for the shortest time. Monitor for sedation and respiratory depression, and consider naloxone availability.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Carisoprodol 的其他交互作用
常見問題
Can I take Benzhydrocodone / acetaminophen with Carisoprodol?
MediHelp rates the interaction as major. Benzhydrocodone / acetaminophen and Carisoprodol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Benzhydrocodone is an opioid prodrug of hydrocodone, and carisoprodol is a sedating muscle relaxant. Together they can produce profound sedation, respiratory depression, coma and death.
How serious is the interaction between Benzhydrocodone / acetaminophen and Carisoprodol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unless other options are inadequate; use the lowest doses for the shortest time. Monitor for sedation and respiratory depression, and consider naloxone availability.
What other medicines interact with Carisoprodol?
MediHelp also lists interactions of Carisoprodol with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Carisoprodol page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
