藥物交互作用
Buprenorphine long-acting + Ethosuximide
嚴重程度: 嚴重
Buprenorphine long-acting and Ethosuximide: major interaction.
最後更新
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摘要
Concurrent use of long-acting injectable buprenorphine with a CNS depressant such as ethosuximide increases the risk of sedation and respiratory depression. The depot effect means the opioid cannot be quickly withdrawn if problems occur.
用白話說明這項交互作用的意義
Buprenorphine long-acting and Ethosuximide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive CNS and respiratory depression.
處置方式
Monitor for oversedation and respiratory depression, particularly after injection and with ethosuximide dose changes. Avoid additional sedatives and alcohol.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Ethosuximide 的其他交互作用
- Benzhydrocodone / acetaminophen + Ethosuximide 嚴重
- Buprenorphine subdermal implant + Ethosuximide 嚴重
- Buprenorphine transdermal + Ethosuximide 嚴重
- Calcium / magnesium / potassium / sodium oxybates + Ethosuximide 嚴重
- Ethosuximide + Fentanyl intranasal 嚴重
- Ethosuximide + Fentanyl iontophoretic transdermal system 嚴重
常見問題
Can I take Buprenorphine long-acting with Ethosuximide?
MediHelp rates the interaction as major. Buprenorphine long-acting and Ethosuximide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Concurrent use of long-acting injectable buprenorphine with a CNS depressant such as ethosuximide increases the risk of sedation and respiratory depression. The depot effect means the opioid cannot be quickly withdrawn if problems occur.
How serious is the interaction between Buprenorphine long-acting and Ethosuximide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for oversedation and respiratory depression, particularly after injection and with ethosuximide dose changes. Avoid additional sedatives and alcohol.
What other medicines interact with Ethosuximide?
MediHelp also lists interactions of Ethosuximide with, for example, Benzhydrocodone / acetaminophen, Buprenorphine subdermal implant, Buprenorphine transdermal. The full list is on the Ethosuximide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
