藥物交互作用
Ciprofloxacin + Thioridazine
嚴重程度: 禁忌併用
Ciprofloxacin and Thioridazine: contraindicated interaction.
最後更新
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摘要
Thioridazine causes marked QT prolongation and is contraindicated with other drugs that prolong the QT interval. Ciprofloxacin adds to this risk of torsades de pointes and sudden death.
用白話說明這項交互作用的意義
Ciprofloxacin and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ciprofloxacin belongs to Anti Bacterial; Thioridazine belongs to Central Nervous System.
為什麼會發生
Additive inhibition of cardiac potassium channels causing delayed repolarization.
處置方式
Avoid the combination and choose an antibiotic without QT effects. If antipsychotic therapy must continue, use a non-QT-prolonging agent for the infection.
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Ciprofloxacin 的其他交互作用
Thioridazine 的其他交互作用
常見問題
Can I take Ciprofloxacin with Thioridazine?
MediHelp rates the interaction as contraindicated. Ciprofloxacin and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Thioridazine causes marked QT prolongation and is contraindicated with other drugs that prolong the QT interval. Ciprofloxacin adds to this risk of torsades de pointes and sudden death.
How serious is the interaction between Ciprofloxacin and Thioridazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose an antibiotic without QT effects. If antipsychotic therapy must continue, use a non-QT-prolonging agent for the infection.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Tizanidine. The full list is on the Ciprofloxacin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
