藥物交互作用
Clemastine + Dextromoramide
嚴重程度: 嚴重
Clemastine and Dextromoramide: major interaction.
最後更新
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摘要
Dextromoramide is a potent opioid, and a sedating antihistamine can substantially add to sedation and psychomotor impairment. Respiratory depression is a risk, especially at higher opioid doses.
用白話說明這項交互作用的意義
Clemastine and Dextromoramide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Additive CNS and respiratory depression from the opioid agonist and the sedating H1 antihistamine.
處置方式
Use the lowest effective doses and monitor for sedation and respiratory depression. Prefer a non-sedating antihistamine and advise avoiding alcohol and driving.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Clemastine 的其他交互作用
常見問題
Can I take Clemastine with Dextromoramide?
MediHelp rates the interaction as major. Clemastine and Dextromoramide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dextromoramide is a potent opioid, and a sedating antihistamine can substantially add to sedation and psychomotor impairment. Respiratory depression is a risk, especially at higher opioid doses.
How serious is the interaction between Clemastine and Dextromoramide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective doses and monitor for sedation and respiratory depression. Prefer a non-sedating antihistamine and advise avoiding alcohol and driving.
What other medicines interact with Clemastine?
MediHelp also lists interactions of Clemastine with, for example, Alfentanil, Benzhydrocodone / acetaminophen, Buprenorphine buccal. The full list is on the Clemastine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
