藥物交互作用
Dengue vaccine + Epirubicin
嚴重程度: 嚴重
Dengue vaccine and Epirubicin: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Dengue vaccine is a live attenuated vaccine. In patients receiving cytotoxic chemotherapy, the immune response may be blunted and the vaccine virus may replicate excessively, causing disease.
用白話說明這項交互作用的意義
Dengue vaccine and Epirubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Chemotherapy-induced immunosuppression reduces vaccine response and permits uncontrolled replication of live vaccine virus.
處置方式
Avoid live vaccines during chemotherapy and give them only after immune recovery, typically at least three months after treatment ends per local guidance. Seek specialist advice if vaccination is needed.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Epirubicin 的其他交互作用
常見問題
Can I take Dengue vaccine with Epirubicin?
MediHelp rates the interaction as major. Dengue vaccine and Epirubicin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Dengue vaccine is a live attenuated vaccine. In patients receiving cytotoxic chemotherapy, the immune response may be blunted and the vaccine virus may replicate excessively, causing disease.
How serious is the interaction between Dengue vaccine and Epirubicin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during chemotherapy and give them only after immune recovery, typically at least three months after treatment ends per local guidance. Seek specialist advice if vaccination is needed.
What other medicines interact with Epirubicin?
MediHelp also lists interactions of Epirubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cimetidine. The full list is on the Epirubicin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
