藥物交互作用
Doxycycline + Microbiota
嚴重程度: 嚴重
Doxycycline and Microbiota: major interaction.
最後更新
僅供醫療專業人員參考。本頁為簡要摘要，並非醫療建議，亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。
本頁的臨床內容僅提供英文版。
摘要
Oral live microbiota products contain bacterial spores that doxycycline can inhibit or kill, reducing colonization and efficacy. Antibiotics should be cleared before dosing.
用白話說明這項交互作用的意義
Doxycycline and Microbiota can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Antibacterial activity of doxycycline against the bacterial spores/organisms in the microbiota product reduces engraftment.
處置方式
Complete the doxycycline course and allow the labeled washout interval (about 2 to 4 days) before giving oral microbiota. Do not start the product while antibiotics are active.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Doxycycline 的其他交互作用
常見問題
Can I take Doxycycline with Microbiota?
MediHelp rates the interaction as major. Doxycycline and Microbiota can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oral live microbiota products contain bacterial spores that doxycycline can inhibit or kill, reducing colonization and efficacy. Antibiotics should be cleared before dosing.
How serious is the interaction between Doxycycline and Microbiota?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete the doxycycline course and allow the labeled washout interval (about 2 to 4 days) before giving oral microbiota. Do not start the product while antibiotics are active.
What other medicines interact with Doxycycline?
MediHelp also lists interactions of Doxycycline with, for example, Acitretin, Aminolevulinic acid, Cholera vaccine. The full list is on the Doxycycline page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
