藥物交互作用
Ethanol + Metformin
嚴重程度: 嚴重
Ethanol and Metformin: major interaction.
最後更新
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摘要
Excessive alcohol intake potentiates the effect of metformin on lactate metabolism and increases the risk of lactic acidosis. Alcohol also increases hypoglycemia risk, especially with fasting.
用白話說明這項交互作用的意義
Ethanol and Metformin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Alcohol impairs hepatic lactate clearance and adds to metformin-related inhibition of gluconeogenesis.
處置方式
Counsel patients to avoid binge or excessive alcohol use; reassess metformin in patients with alcohol use disorder.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Metformin 的其他交互作用
常見問題
Can I take Ethanol with Metformin?
MediHelp rates the interaction as major. Ethanol and Metformin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Excessive alcohol intake potentiates the effect of metformin on lactate metabolism and increases the risk of lactic acidosis. Alcohol also increases hypoglycemia risk, especially with fasting.
How serious is the interaction between Ethanol and Metformin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid binge or excessive alcohol use; reassess metformin in patients with alcohol use disorder.
What other medicines interact with Metformin?
MediHelp also lists interactions of Metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Metformin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
