藥物交互作用
Ethanol + Vitamin b1
嚴重程度: 嚴重
Ethanol and Vitamin b1: major interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Chronic alcohol use impairs thiamine absorption, storage and utilization, and poor diet adds to the risk. This can lead to deficiency, Wernicke encephalopathy and Korsakoff syndrome.
用白話說明這項交互作用的意義
Ethanol and Vitamin b1 can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
為什麼會發生
Alcohol inhibits intestinal thiamine transport, reduces hepatic storage and conversion to active forms, and increases loss.
處置方式
Give thiamine to patients with alcohol use disorder, using parenteral dosing when Wernicke encephalopathy is suspected, and give it before glucose.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Vitamin b1 的其他交互作用
常見問題
Can I take Ethanol with Vitamin b1?
MediHelp rates the interaction as major. Ethanol and Vitamin b1 can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Chronic alcohol use impairs thiamine absorption, storage and utilization, and poor diet adds to the risk. This can lead to deficiency, Wernicke encephalopathy and Korsakoff syndrome.
How serious is the interaction between Ethanol and Vitamin b1?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give thiamine to patients with alcohol use disorder, using parenteral dosing when Wernicke encephalopathy is suspected, and give it before glucose.
What other medicines interact with Vitamin b1?
MediHelp also lists interactions of Vitamin b1 with, for example, Bumetanide, Ethacrynic acid, Furosemide. The full list is on the Vitamin b1 page.
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