藥物交互作用
Ifosfamide + Measles mumps and rubella vaccine
嚴重程度: 禁忌併用
Ifosfamide and Measles mumps and rubella vaccine: contraindicated interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Ifosfamide is a cytotoxic alkylating agent that depletes lymphocytes and neutrophils, so live attenuated measles, mumps, rubella and varicella vaccine viruses may replicate without control. This can lead to disseminated vaccine-strain disease and the vaccine also gives poor protection.
用白話說明這項交互作用的意義
Ifosfamide and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ifosfamide belongs to Oncology; Measles mumps and rubella vaccine belongs to Miscellaneous.
為什麼會發生
Immunosuppression permits replication of live attenuated vaccine viruses: myelosuppression and lymphocyte depletion
處置方式
Do not give live vaccines during chemotherapy; vaccinate at least 4 weeks before starting and defer until immune recovery (usually at least 3 months after treatment ends).
可向藥師詢問的問題
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Measles mumps and rubella vaccine 的其他交互作用
- Adalimumab + Measles mumps and rubella vaccine 禁忌併用
- Anakinra + Measles mumps and rubella vaccine 禁忌併用
- Antithymocyte globulin equine + Measles mumps and rubella vaccine 禁忌併用
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine 禁忌併用
- Azathioprine + Measles mumps and rubella vaccine 禁忌併用
- Basiliximab + Measles mumps and rubella vaccine 禁忌併用
Ifosfamide 的其他交互作用
常見問題
Can I take Ifosfamide with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Ifosfamide and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ifosfamide is a cytotoxic alkylating agent that depletes lymphocytes and neutrophils, so live attenuated measles, mumps, rubella and varicella vaccine viruses may replicate without control. This can lead to disseminated vaccine-strain disease and the vaccine also gives poor protection.
How serious is the interaction between Ifosfamide and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during chemotherapy; vaccinate at least 4 weeks before starting and defer until immune recovery (usually at least 3 months after treatment ends).
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
