藥物交互作用
Metformin-pioglitazone + Patiromer
嚴重程度: 中度
Metformin-pioglitazone and Patiromer: moderate interaction.
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摘要
Patiromer is a non-absorbed polymer that can bind coadministered oral drugs in the gut. This may lower metformin absorption and weaken glycemic control.
用白話說明這項交互作用的意義
Metformin-pioglitazone and Patiromer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Metformin-pioglitazone belongs to Endocrine; Patiromer belongs to Miscellaneous.
為什麼會發生
Binding of metformin in the gastrointestinal tract by patiromer reduces absorption.
處置方式
Give metformin at least 3 hours before or after patiromer. Monitor blood glucose.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Metformin-pioglitazone 的其他交互作用
Patiromer 的其他交互作用
常見問題
Can I take Metformin-pioglitazone with Patiromer?
MediHelp rates the interaction as moderate. Metformin-pioglitazone and Patiromer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Patiromer is a non-absorbed polymer that can bind coadministered oral drugs in the gut. This may lower metformin absorption and weaken glycemic control.
How serious is the interaction between Metformin-pioglitazone and Patiromer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give metformin at least 3 hours before or after patiromer. Monitor blood glucose.
What other medicines interact with Metformin-pioglitazone?
MediHelp also lists interactions of Metformin-pioglitazone with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Metformin-pioglitazone page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。