Diseases
paget's disease
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Paget's (PAJ-its) disease of bone interferes with your body's normal recycling process, in which new bone tissue gradually replaces old bone tissue. Over time, bones can become fragile and misshapen. The pelvis, skull, spine and legs are most commonly affected.
Symptoms
- paget's disease of bone in the pelvis can cause hip pain.
- an overgrowth of bone in the skull can cause hearing loss or headaches.
- pain, tingling and numbness in an arm or leg.
- leg. as the bones weaken, they may bend — causing you to become bowlegged.
Causes
- the cause of paget's disease of bone is unknown. scientists suspect a combination of environmental and genetic factors contribute to the disease.
- some scientists believe paget's disease of bone is related to a viral infection in your bone cells,
- but this theory is controversial.
Risk factors
- people older than 50 are most likely to develop the disease.
- men are more commonly affected than are women.
- paget's disease of bone is more common in england, scotland, central europe and
Diagnosis
- imaging tests, ie, bone scan, and x-rays
- lab tests
Medicines used
Frequently asked questions
What is paget's disease?
Paget's (PAJ-its) disease of bone interferes with your body's normal recycling process, in which new bone tissue gradually replaces old bone tissue. Over time, bones can become fragile and misshapen. The pelvis, skull, spine and legs are most commonly affected.
What are the symptoms of paget's disease?
paget's disease of bone in the pelvis can cause hip pain., an overgrowth of bone in the skull can cause hearing loss or headaches., pain, tingling and numbness in an arm or leg., leg. as the bones weaken, they may bend — causing you to become bowlegged.
What causes paget's disease?
the cause of paget's disease of bone is unknown. scientists suspect a combination of environmental and genetic factors contribute to the disease.; some scientists believe paget's disease of bone is related to a viral infection in your bone cells,; but this theory is controversial.
Which medicines are used for paget's disease?
alendronate, calcitonin, etidronate, pamidronate, risedronate, tiludronate, zoledronic acid
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