Drug reference
zoledronic acid
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (Bisphosphonate)
Mechanism of action
Bisphosphonate; inhibits bone resorption via actions on osteoclast activity, leading to indirect increase in bone density
Common side effects
- Constipation
- Anemia
- Vomiting
- Fatigue
- Nausea
- Bone pain
- Fever
Contraindications
- Pregnancy All indications: Hypersensitivity, including rare cases of urticaria, angioedema, and anaphylactic reaction or shock Nononcologic uses: Hypocalcemia, severe renal impairment (CrCl <35 mL/min or evidence of acute renal impairment)
Related conditions
Frequently asked questions
What drug class is zoledronic acid?
zoledronic acid belongs to: Musculoskeletal.
How does zoledronic acid work?
Bisphosphonate; inhibits bone resorption via actions on osteoclast activity, leading to indirect increase in bone density
What are the common side effects of zoledronic acid?
Constipation, Anemia, Vomiting, Fatigue, Nausea, Bone pain, Fever
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