Drug reference
abciximab
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Anti Platelets)
Mechanism of action
Chimeric monoclonal antibody; prevents binding of fibrinogen, vWF to glycoprotein IIb/IIIa receptor sites on platelets
Common side effects
- Vomiting
- Nausea
- Bleeding
- Back pain
- Chest pain
- Hypotension
Contraindications
- Recent (within six weeks) gastrointestinal (GI) or genitourinary (GU) bleeding of clinical significance
- History of CVA (within 2 years) or CVA with a significant residual neurological deficit
- Administration of oral anticoagulants within seven days unless prothrombin time is ≤1.2 times control
- Intracranial neoplasm, arteriovenous malformation, or aneurysm Severe uncontrolled hypertension Presumed or documented history of vasculitis
Known interactions (5)
- abciximab + argatroban Major
- abciximab + dalteparin Major
- abciximab + enoxaparin Major
- abciximab + fondaparinux Major
- abciximab + heparin Moderate
Related conditions
Frequently asked questions
What drug class is abciximab?
abciximab belongs to: Cardiovascular.
How does abciximab work?
Chimeric monoclonal antibody; prevents binding of fibrinogen, vWF to glycoprotein IIb/IIIa receptor sites on platelets
What are the common side effects of abciximab?
Vomiting, Nausea, Bleeding, Back pain, Chest pain, Hypotension
Which drugs interact with abciximab?
argatroban, dalteparin, enoxaparin, fondaparinux, heparin
Full monographs, dosing and an interaction checker in the MediHelp app
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