Drug reference

adenosine

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Cardiovascular (Anti Arrhythmia)

Mechanism of action

PSVT: Slows conduction through AV node and interrupts AV reentry pathways, which restore normal sinus symptoms

Stress testing: A2A adenosine receptor agonist; activation of the A2A adenosine receptor produces coronary vasodilation and increases coronary blood flow

Common side effects

  • Lightheadedness
  • Dyspnea
  • Flushing
  • Tingling
  • Chest tightness
  • Numbness

Contraindications

  • 2nd or 3rd degree AV block (except those on pacemakers)
  • Sinus node disease, such as sick sinus syndrome or symptomatic bradycardia (except in patients with a functioning artificial pacemaker)
  • Adenoscan: Contraindicated in bronchoconstrictive or bronchospastic lung disease (eg, asthma)

Related conditions

Frequently asked questions

What drug class is adenosine?

adenosine belongs to: Cardiovascular.

How does adenosine work?

PSVT: Slows conduction through AV node and interrupts AV reentry pathways, which restore normal sinus symptoms Stress testing: A2A adenosine receptor agonist; activation of the A2A adenosine receptor produces coronary vasodilation and increases coronary blood flow

What are the common side effects of adenosine?

Lightheadedness, Dyspnea, Flushing, Tingling, Chest tightness, Numbness

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