Drug reference
magnesium sulphate
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Anti Arrhythmia)
Mechanism of action
Depresses CNS, blocks peripheral neuromuscular transmission, produces anticonvulsant effects; decreases amount of acetylcholine released at end-plate by motor nerve impulse Slows rate of SA node impulse formation in myocardium and prolongs conduction time
Common side effects
- Circulatory collapse
- Pulmonary edema
- Respiratory paralysis
- Hypothermia
- Depressed reflexes
Contraindications
- Hypersensitivity Myocardial damage, diabetic coma, heart block Hypermagnesemia Hypercalcemia Administration during 2 hours preceding delivery for mothers with toxemia of pregnancy
Known interactions (1)
- eltrombopag + magnesium sulphate Moderate
Related conditions
Frequently asked questions
What drug class is magnesium sulphate?
magnesium sulphate belongs to: Cardiovascular.
How does magnesium sulphate work?
Depresses CNS, blocks peripheral neuromuscular transmission, produces anticonvulsant effects; decreases amount of acetylcholine released at end-plate by motor nerve impulse Slows rate of SA node impulse formation in myocardium and prolongs conduction time
What are the common side effects of magnesium sulphate?
Circulatory collapse, Pulmonary edema, Respiratory paralysis, Hypothermia, Depressed reflexes
Which drugs interact with magnesium sulphate?
eltrombopag
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