Drug reference

atropine

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Miscellaneous (Miscellaneous)

Mechanism of action

Blocks the action of acetylcholine resulting in relaxation of the cholinergically innervated sphincter muscle of the iris. Cholinergic stimulation of the accommodative ciliary muscle of the lens is also blocked. Anticholinergic effects of atropine sulfate in the eye produce dilation of the pupil (mydriasis) and paralysis of accommodation.

Common side effects

  • Insomnia
  • Dry mouth
  • Headache
  • Fever
  • Ataxia

Known interactions (1)

Related conditions

Frequently asked questions

What drug class is atropine?

atropine belongs to: Miscellaneous.

How does atropine work?

Blocks the action of acetylcholine resulting in relaxation of the cholinergically innervated sphincter muscle of the iris. Cholinergic stimulation of the accommodative ciliary muscle of the lens is also blocked. Anticholinergic effects of atropine sulfate in the eye produce dilation of the pupil (mydriasis) and paralysis of accommodation.

What are the common side effects of atropine?

Insomnia, Dry mouth, Headache, Fever, Ataxia

Which drugs interact with atropine?

epinephrine

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug reference