Drug reference
crizotinib
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Oncology (Anti Neoplastics)
Mechanism of action
Inhibitor of receptor tyrosine kinases including ALK, Hepatocyte Growth Factor Receptor (HGFR, c-Met), and Recepteur d’Origine Nantais (RON). ALK gene expression and signaling that contribute to increased cell proliferation and survival of the tumors become activated following formation of ALK oncogenic fusion proteins.
Common side effects
- Constipation
- Vomiting
- Edema
- Nausea
- Vision disorders
- Elevated transaminases
- Diarrhea
Related conditions
Frequently asked questions
What drug class is crizotinib?
crizotinib belongs to: Oncology.
How does crizotinib work?
Inhibitor of receptor tyrosine kinases including ALK, Hepatocyte Growth Factor Receptor (HGFR, c-Met), and Recepteur d’Origine Nantais (RON). ALK gene expression and signaling that contribute to increased cell proliferation and survival of the tumors become activated following formation of ALK oncogenic fusion proteins.
What are the common side effects of crizotinib?
Constipation, Vomiting, Edema, Nausea, Vision disorders, Elevated transaminases, Diarrhea
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