Drug reference
daratumumab
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Oncology (Monoclonal antibody(Oncology))
Mechanism of action
Monoclonal antibody that binds with high affinity to the CD38 molecule, which is highly expressed on the surface of multiple myeloma cells. Binding to CD38 is believed to induce rapid tumor cell death through programmed cell death, or apoptosis, and multiple immune-mediated mechanisms, including complement-dependent cytotoxicity.
Common side effects
- Neutropenia
- Anemia
- Fatigue
- Thrombocytopenia
- Lymphopenia
- Infusion reaction
Related conditions
Frequently asked questions
What drug class is daratumumab?
daratumumab belongs to: Oncology.
How does daratumumab work?
Monoclonal antibody that binds with high affinity to the CD38 molecule, which is highly expressed on the surface of multiple myeloma cells. Binding to CD38 is believed to induce rapid tumor cell death through programmed cell death, or apoptosis, and multiple immune-mediated mechanisms, including complement-dependent cytotoxicity.
What are the common side effects of daratumumab?
Neutropenia, Anemia, Fatigue, Thrombocytopenia, Lymphopenia, Infusion reaction
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.