Drug reference
dimethyl fumarate
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (MS Drugs)
Mechanism of action
Exact mechanism is unknown Methyl ester of fumaric acid that elicits immunomodulatory effects Dimethyl fumarate and the metabolite (monomethyl fumarate [MMF]) activates the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway, a transcription factor encoded by the NFE2L2 gene
Common side effects
- Pruritus
- Rash
- Vomiting
- Nausea
- Abdominal pain
- Diarrhea
Related conditions
Frequently asked questions
What drug class is dimethyl fumarate?
dimethyl fumarate belongs to: Central Nervous System.
How does dimethyl fumarate work?
Exact mechanism is unknown Methyl ester of fumaric acid that elicits immunomodulatory effects Dimethyl fumarate and the metabolite (monomethyl fumarate [MMF]) activates the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway, a transcription factor encoded by the NFE2L2 gene
What are the common side effects of dimethyl fumarate?
Pruritus, Rash, Vomiting, Nausea, Abdominal pain, Diarrhea
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.