Drug reference

mitoxantrone

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Central Nervous System (MS Drugs)

Mechanism of action

Anthracenedione; DNA-reactive agent with cell cycle nonspecific cytocidal activity that intercalates into DNA resulting in cross-links and strand breaks; inhibits DNA and RNA synthesis

Common side effects

  • Upper respiratory tract infection
  • Alopecia
  • Nausea
  • Amenorrhea
  • Stomatitis
  • Urinary tract infection
  • Diarrhea

Related conditions

Frequently asked questions

What drug class is mitoxantrone?

mitoxantrone belongs to: Central Nervous System.

How does mitoxantrone work?

Anthracenedione; DNA-reactive agent with cell cycle nonspecific cytocidal activity that intercalates into DNA resulting in cross-links and strand breaks; inhibits DNA and RNA synthesis

What are the common side effects of mitoxantrone?

Upper respiratory tract infection, Alopecia, Nausea, Amenorrhea, Stomatitis, Urinary tract infection, Diarrhea

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