Drug reference
hydrocodone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (Opioids)
Mechanism of action
Mu opioid receptor agonist; interacts with other opioid receptors at higher doses; activates opioid receptors at sites in the peri-aquaductal and peri-ventricular gray matter, the ventro-medial medulla and the spinal cord to produce analgesia, Also elicits euphoric, respiratory depressant, and physiologic dependence properties of mu receptors
Common side effects
- Dry mouth
- Constipation
- Vomiting
- Somnolence
- Nausea
- UTI
Contraindications
- Hypersensitivity Significant respiratory depression Acute or severe bronchial asthma or hypercarbia Suspected paralytic ileus
Related conditions
Frequently asked questions
What drug class is hydrocodone?
hydrocodone belongs to: Musculoskeletal.
How does hydrocodone work?
Mu opioid receptor agonist; interacts with other opioid receptors at higher doses; activates opioid receptors at sites in the peri-aquaductal and peri-ventricular gray matter, the ventro-medial medulla and the spinal cord to produce analgesia, Also elicits euphoric, respiratory depressant, and physiologic dependence properties of mu receptors
What are the common side effects of hydrocodone?
Dry mouth, Constipation, Vomiting, Somnolence, Nausea, UTI
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