Drug reference

hydromorphone

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Musculoskeletal (Opioids)

Mechanism of action

Mu-opioid receptor agonist; inhibits ascending pain pathways, thus altering response to pain; main therapeutic action is analgesia, Other pharmacologic effects include respiratory depression and sedation; suppresses cough by acting centrally in medulla.

Common side effects

  • Palpitations
  • Constipation
  • Sedation
  • Angina pectoris
  • Urinary retention
  • Dysphoria
  • Tachycardia

Related conditions

Frequently asked questions

What drug class is hydromorphone?

hydromorphone belongs to: Musculoskeletal.

How does hydromorphone work?

Mu-opioid receptor agonist; inhibits ascending pain pathways, thus altering response to pain; main therapeutic action is analgesia, Other pharmacologic effects include respiratory depression and sedation; suppresses cough by acting centrally in medulla.

What are the common side effects of hydromorphone?

Palpitations, Constipation, Sedation, Angina pectoris, Urinary retention, Dysphoria, Tachycardia

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug reference