Drug reference
hydroxyzine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Respiratory (Anti Histamine)
Mechanism of action
Hydroxyzine competes with histamine for the histamine H1 receptor, reversible competitive inhibitor.
Common side effects
- Sedation
- Drowsiness
- Nausea
- Upset Stomach
Contraindications
- Documented hypersensitivity or related product including cetirizine and levocetirizine and components of the formulation Prolonged QT interval SC, intra-arterial, or IV administration
Known interactions (4)
- hydroxyzine + pimozide Contraindicated
- hydroxyzine + thioridazine Contraindicated
- dronedarone + hydroxyzine Major
- Dexamethasone + hydroxyzine Moderate
Related conditions
Frequently asked questions
What drug class is hydroxyzine?
hydroxyzine belongs to: Respiratory.
How does hydroxyzine work?
Hydroxyzine competes with histamine for the histamine H1 receptor, reversible competitive inhibitor.
What are the common side effects of hydroxyzine?
Sedation, Drowsiness, Nausea, Upset Stomach
Which drugs interact with hydroxyzine?
pimozide, thioridazine, dronedarone, Dexamethasone
Full monographs, dosing and an interaction checker in the MediHelp app
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