Drug reference
linezolid
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Bacterial (Miscellaneous(Anti Bacterial))
Mechanism of action
Binds to bacterial 23S rRNA of the 50S subunit to prevent protein translation; also elicits nonselective MAO inhibition
Common side effects
- Dizziness
- Vomiting
- Headache
- Nausea
- Fungal infection
- Diarrhea
Contraindications
- Hypersensitivity Within 14 days of taking MAO inhibitor
Known interactions (30)
- atomoxetine + linezolid Contraindicated
- brimonidine + linezolid Contraindicated
- buspirone + linezolid Contraindicated
- dextroamphetamine + linezolid Contraindicated
- dextromethorphan + linezolid Contraindicated
- duloxetine + linezolid Contraindicated
- adrenaline-articaine + linezolid Major
- almotriptan + linezolid Major
- budesonide-formoterol + linezolid Major
- carbamazepine + linezolid Major
- citalopram + linezolid Major
- cyproheptadine + linezolid Major
- desvenlafaxine + linezolid Major
- dobutamine + linezolid Major
- dopamine + linezolid Major
- dosulepin + linezolid Major
- eletriptan + linezolid Major
- epinephrine + linezolid Major
- fluoxetine + linezolid Major
- frovatriptan + linezolid Major
- linezolid + meperidine Major
- linezolid + sertraline Major
- linezolid + tyramine-containing drugs (e.g., selegiline) Major
- armodafinil + linezolid Moderate
- caffeine + linezolid Moderate
- fluticasone-salmeterol + linezolid Moderate
- formoterol + linezolid Moderate
- formoterol-mometasone + linezolid Moderate
- ipratropium-salbutamol + linezolid Moderate
- isoproterenol + linezolid Moderate
Related conditions
Frequently asked questions
What drug class is linezolid?
linezolid belongs to: Anti Bacterial.
How does linezolid work?
Binds to bacterial 23S rRNA of the 50S subunit to prevent protein translation; also elicits nonselective MAO inhibition
What are the common side effects of linezolid?
Dizziness, Vomiting, Headache, Nausea, Fungal infection, Diarrhea
Which drugs interact with linezolid?
atomoxetine, brimonidine, buspirone, dextroamphetamine, dextromethorphan, duloxetine, adrenaline-articaine, almotriptan, budesonide-formoterol, carbamazepine, citalopram, cyproheptadine, desvenlafaxine, dobutamine, dopamine
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