Drug reference
loperamide
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Gastrointestinal Tract (Anti Motility)
Mechanism of action
Slows intestinal motility through opioid receptor; has direct effects on circular and longitudinal muscle; reduces fecal volume; increases viscosity.
Common side effects
- Increase risk of Toxic Megacolon
- Flatulence
- Dizziness
- Stomach cramps.
- Abdominal pain
Known interactions (2)
- hydroxychloroquine + loperamide Moderate
- levofloxacin + loperamide Moderate
Related conditions
Frequently asked questions
What drug class is loperamide?
loperamide belongs to: Gastrointestinal Tract.
How does loperamide work?
Slows intestinal motility through opioid receptor; has direct effects on circular and longitudinal muscle; reduces fecal volume; increases viscosity.
What are the common side effects of loperamide?
Increase risk of Toxic Megacolon, Flatulence, Dizziness, Stomach cramps., Abdominal pain
Which drugs interact with loperamide?
hydroxychloroquine, levofloxacin
Full monographs, dosing and an interaction checker in the MediHelp app
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