Drug reference

pioglitazone

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Insulin sensitizers)

Mechanism of action

Improves target-cell response to insulin; decreases hepatic gluconeogenesis; depends on the presence of insulin for activity

Common side effects

  • Headache
  • Hypoglycemia
  • Edema when used in combination with sulfonylurea
  • Sinusitis
  • Heart failure

Related conditions

Frequently asked questions

What drug class is pioglitazone?

pioglitazone belongs to: Endocrine.

How does pioglitazone work?

Improves target-cell response to insulin; decreases hepatic gluconeogenesis; depends on the presence of insulin for activity

What are the common side effects of pioglitazone?

Headache, Hypoglycemia, Edema when used in combination with sulfonylurea, Sinusitis, Heart failure

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