Drug reference

rosiglitazone

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Endocrine (Insulin sensitizers)

Mechanism of action

Lowers glucose by improving target cell response to insulin without increasing pancreatic cell secretion; activates nuclear peroxisome proliferator-activated receptor gamma, which influences the production of gene products involved in glucose and lipid metabolism

Common side effects

  • Edema
  • Increased LDL-cholesterol
  • Hypertension
  • Increased HDL-cholesterol
  • Increased total cholesterol
  • Heart failure/congestive heart failure
  • Myocardial ischemia

Related conditions

Frequently asked questions

What drug class is rosiglitazone?

rosiglitazone belongs to: Endocrine.

How does rosiglitazone work?

Lowers glucose by improving target cell response to insulin without increasing pancreatic cell secretion; activates nuclear peroxisome proliferator-activated receptor gamma, which influences the production of gene products involved in glucose and lipid metabolism

What are the common side effects of rosiglitazone?

Edema, Increased LDL-cholesterol, Hypertension, Increased HDL-cholesterol, Increased total cholesterol, Heart failure/congestive heart failure, Myocardial ischemia

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