Drug reference

nicorandil

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Drug class

Cardiovascular (Anti Anginal)

Mechanism of action

Nicorandil relaxes coronary vascular smooth muscle by stimulating guanylyl cyclase and increasing cyclic GMP (cGMP) levels (as shown first in our laboratory) as well as by a second mechanism resulting in activation of K+ channels and hyperpolarization.

Common side effects

  • Dizziness
  • Headache
  • Abscess
  • Heart rate increased

Related conditions

Frequently asked questions

What drug class is nicorandil?

nicorandil belongs to: Cardiovascular.

How does nicorandil work?

Nicorandil relaxes coronary vascular smooth muscle by stimulating guanylyl cyclase and increasing cyclic GMP (cGMP) levels (as shown first in our laboratory) as well as by a second mechanism resulting in activation of K+ channels and hyperpolarization.

What are the common side effects of nicorandil?

Dizziness, Headache, Abscess, Heart rate increased

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