Drug reference
rofecoxib
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (NSAIDs)
Mechanism of action
Inhibits cyclooxygenase (COX)-2; does not affect COX-1 (at therapeutic concentrations), thereby decreasing formation of prostaglandin synthesis.
Common side effects
- Heart attack
- Stroke
Related conditions
Frequently asked questions
What drug class is rofecoxib?
rofecoxib belongs to: Musculoskeletal.
How does rofecoxib work?
Inhibits cyclooxygenase (COX)-2; does not affect COX-1 (at therapeutic concentrations), thereby decreasing formation of prostaglandin synthesis.
What are the common side effects of rofecoxib?
Heart attack, Stroke
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