Drug reference
celecoxib
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (NSAIDs)
Mechanism of action
Inhibits cyclooxygenase (COX)-2; does not affect COX-1 (at therapeutic concentrations), thereby decreasing formation of prostaglandin synthesis.
Common side effects
- Upper respiratory tract infection
- Dyspepsia
- Arthralgia
- Headache
- Fever
- Hypertension
Contraindications
- Known hypersensitivity (eg, anaphylactic reactions, serious skin reactions) to celecoxib or its components History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs; severe, sometimes fata, anaphylactic reactions reported In the setting of coronary ar…
Known interactions (4)
- celecoxib + Diclofenac Major
- celecoxib + Naproxen Major
- celecoxib + Rivaroxaban Major
- celecoxib + Sulindac Major
Related conditions
Frequently asked questions
What drug class is celecoxib?
celecoxib belongs to: Musculoskeletal.
How does celecoxib work?
Inhibits cyclooxygenase (COX)-2; does not affect COX-1 (at therapeutic concentrations), thereby decreasing formation of prostaglandin synthesis.
What are the common side effects of celecoxib?
Upper respiratory tract infection, Dyspepsia, Arthralgia, Headache, Fever, Hypertension
Which drugs interact with celecoxib?
Diclofenac, Naproxen, Rivaroxaban, Sulindac
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