Drug reference
sodium polystyrene sulfonate
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Miscellaneous (Miscellaneous)
Mechanism of action
Cation exchange resin, sodium ions partially released from polystyrene and replaced by potassium
Common side effects
- Constipation
- Sodium retention, Fluid retention.
- Nausea and Vomiting
- Hypokalemia
- Hypomagnesemia
Contraindications
- Hypersensitivity to polystyrene sulfonate resins Hypokalemia Obstructive bowel disease
- Neonates with reduced gut motility (postoperative or drug-induced), oral administration
- Rectal administration of suspension with sorbitol in neonates, particularly in premature infants
Related conditions
Frequently asked questions
What drug class is sodium polystyrene sulfonate?
sodium polystyrene sulfonate belongs to: Miscellaneous.
How does sodium polystyrene sulfonate work?
Cation exchange resin, sodium ions partially released from polystyrene and replaced by potassium
What are the common side effects of sodium polystyrene sulfonate?
Constipation, Sodium retention, Fluid retention., Nausea and Vomiting, Hypokalemia, Hypomagnesemia
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