Drug reference
sofosbuvir-velpatasvir-voxilaprevir
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Virals (Hepatits Viruses)
Mechanism of action
Sofosbuvir: Inhibitor of HCV NS5B RNA-dependent polymerase. Velpatasvir: Pangenotypic HCV NS5A inhibitor. Voxilaprevir: Pangenotypic NS3/4A protease inhibitor, which is needed for proteolytic cleavage of the HCV-encoded polyprotein into mature forms and is essential for viral replication.
Common side effects
- Headache
- Fatigue
- Nausea
- Diarrhea
Contraindications
- Rifampin; significantly decreases sofosbuvir, velpatasvir, and voxilaprevir serum concentrations
Known interactions (2)
Related conditions
Frequently asked questions
What drug class is sofosbuvir-velpatasvir-voxilaprevir?
sofosbuvir-velpatasvir-voxilaprevir belongs to: Anti Virals.
How does sofosbuvir-velpatasvir-voxilaprevir work?
Sofosbuvir: Inhibitor of HCV NS5B RNA-dependent polymerase. Velpatasvir: Pangenotypic HCV NS5A inhibitor. Voxilaprevir: Pangenotypic NS3/4A protease inhibitor, which is needed for proteolytic cleavage of the HCV-encoded polyprotein into mature forms and is essential for viral replication.
What are the common side effects of sofosbuvir-velpatasvir-voxilaprevir?
Headache, Fatigue, Nausea, Diarrhea
Which drugs interact with sofosbuvir-velpatasvir-voxilaprevir?
carbamazepine, colchicine
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