Drug interactions
Alprazolam + Butabarbital
Severity: Moderate
Alprazolam and Butabarbital: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Butabarbital adds to the sedative effect of alprazolam and may also lower alprazolam exposure by inducing its metabolism.
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to see why Alprazolam and Butabarbital interact, what to do about it, and the sources.
- Mechanism of action
- Clinical management
- Evidence level
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Alprazolam
- Alprazolam + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Alprazolam + Itraconazole Contraindicated
- Alprazolam + Ketoconazole Contraindicated
Drug class
- Alprazolam
- Central Nervous System
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.