Drug interactions
Alprazolam + Clonidine
Severity: Moderate
Alprazolam and Clonidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have sedative effects, so combined use can increase drowsiness, dizziness and psychomotor impairment, and may add to blood pressure lowering.
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Other interactions of Clonidine
- Acebutolol + Clonidine Major
- Amifostine + Clonidine Major
Other interactions of Alprazolam
- Alprazolam + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Alprazolam + Itraconazole Contraindicated
- Alprazolam + Ketoconazole Contraindicated
Drug class
- Alprazolam
- Central Nervous System
- Clonidine
- Cardiovascular
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