Drug interactions
Alprazolam + Motherwort
Severity: Minor
Alprazolam and Motherwort: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Motherwort has traditional sedative properties, so combining it with alprazolam may add to drowsiness. Supporting data are limited.
What this interaction means in plain words
Alprazolam and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive sedation; mechanism is not well established.
What to do
Advise patients to watch for increased drowsiness and avoid driving if affected.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Alprazolam
- Alprazolam + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Alprazolam + Itraconazole Contraindicated
- Alprazolam + Ketoconazole Contraindicated
- Alprazolam + Levoketoconazole Contraindicated
- Alprazolam + Sodium oxybate Contraindicated
- Alfentanil + Alprazolam Major
Frequently asked questions
Can I take Alprazolam with Motherwort?
MediHelp rates the interaction as minor. Alprazolam and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort has traditional sedative properties, so combining it with alprazolam may add to drowsiness. Supporting data are limited.
How serious is the interaction between Alprazolam and Motherwort?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for increased drowsiness and avoid driving if affected.
What other medicines interact with Alprazolam?
MediHelp also lists interactions of Alprazolam with, for example, Calcium / magnesium / potassium / sodium oxybates, Itraconazole, Ketoconazole. The full list is on the Alprazolam page.
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