Drug interactions
Alprazolam + Teduglutide
Severity: Minor
Alprazolam and Teduglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide improves intestinal fluid and nutrient absorption and may increase the absorption of oral drugs such as alprazolam. This could raise alprazolam levels and sedation in some patients.
What this interaction means in plain words
Alprazolam and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Alprazolam belongs to Central Nervous System; Teduglutide belongs to Endocrine.
Why it happens
Increased intestinal absorption of orally administered drugs due to teduglutide's intestinotrophic effects.
What to do
Monitor for excess sedation when starting teduglutide and reduce the alprazolam dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Alprazolam
- Alprazolam + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Alprazolam + Itraconazole Contraindicated
- Alprazolam + Ketoconazole Contraindicated
- Alprazolam + Levoketoconazole Contraindicated
- Alprazolam + Sodium oxybate Contraindicated
- Alfentanil + Alprazolam Major
Frequently asked questions
Can I take Alprazolam with Teduglutide?
MediHelp rates the interaction as minor. Alprazolam and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Teduglutide improves intestinal fluid and nutrient absorption and may increase the absorption of oral drugs such as alprazolam. This could raise alprazolam levels and sedation in some patients.
How serious is the interaction between Alprazolam and Teduglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excess sedation when starting teduglutide and reduce the alprazolam dose if needed.
What other medicines interact with Alprazolam?
MediHelp also lists interactions of Alprazolam with, for example, Calcium / magnesium / potassium / sodium oxybates, Itraconazole, Ketoconazole. The full list is on the Alprazolam page.
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