Drug interactions
Alteplase + Diclofenac
Severity: Major
Alteplase and Diclofenac: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Diclofenac inhibits platelet function and can irritate the gastric mucosa, which may increase bleeding risk when a thrombolytic such as alteplase is given.
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Other interactions of Diclofenac
Other interactions of Alteplase
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