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Drug interactions

Alteplase + Fondaparinux

Severity: Major

Alteplase and Fondaparinux: major interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Alteplase lyses clots and combined with fondaparinux markedly increases the chance of serious bleeding, including intracranial hemorrhage.

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