Drug interactions
Alteplase + Mefenamic acid
Severity: Major
Alteplase and Mefenamic acid: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
NSAIDs impair platelet function and can irritate the gastric mucosa, which adds to the bleeding risk from thrombolysis with alteplase.
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Other interactions of Mefenamic acid
Other interactions of Alteplase
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